Karyopharm Therapeutics (NASDAQ: KPTI) insider transactions
In the twelve months to 10 November 2026, executives and directors of Karyopharm Therapeutics reported 21 open-market sales of 43,016 shares ($351,422) and 0 open-market purchases, by 7 people, according to the Form 4 filings they submitted to the SEC.
Latest transactions
| Date | Insider | Role | Transaction | Shares | Price | Held after | Filing |
|---|---|---|---|---|---|---|---|
| 16 October 2026 | Abate Kristin | Chief Accounting Officer | Open-market sale | −4,788 | $0.34 | 18,616 | Form 4 |
| 1 October 2026 | Abate Kristin | Chief Accounting Officer | Open-market sale | −378 | $1.19 | 23,404 | Form 4 |
| 1 September 2026 | Abate Kristin | Chief Accounting Officer | Open-market sale | −19 | $2.02 | 23,782 | Form 4 |
| 28 July 2026 | Poulton Stuart | EVP, Chief Development Officer | Open-market sale | −189 | $7.10 | 94,632 | Form 4 |
| 21 May 2026 | Bohlin Garen G | Director | Grant or award | +15,508 | — | 18,517 | Form 4 |
| 21 May 2026 | Pakianathan Deepika | Director | Grant or award | +15,508 | — | 15,508 | Form 4 |
| 21 May 2026 | Greene Barry E | Director | Grant or award | +15,508 | — | 16,415 | Form 4 |
| 21 May 2026 | Schor Chen | Director | Grant or award | +15,508 | — | 15,508 | Form 4 |
| 21 May 2026 | Oliger Christy J. | Director | Grant or award | +15,508 | — | 15,508 | Form 4 |
| 21 May 2026 | Su Zhen | Director | Grant or award | +15,508 | — | 15,508 | Form 4 |
| 14 May 2026 | Mano Michael | EVP, CLO&Secretary | Open-market sale | −266 | $9.50 | 94,398 | Form 4 |
| 14 May 2026 | Paulson Richard A. | President and CEO | Open-market sale | −2,203 | $9.50 | 269,747 | Form 4 |
| 14 May 2026 | Abate Kristin | Chief Accounting Officer | Open-market sale | −53 | $9.50 | 23,801 | Form 4 |
| 14 May 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Open-market sale | −324 | $9.50 | 107,940 | Form 4 |
| 14 May 2026 | Rangwala Reshma | EVP & Chief Medical Officer | Open-market sale | −408 | $9.50 | 56,829 | Form 4 |
| 14 May 2026 | Poulton Stuart | EVP, Chief Development Officer | Open-market sale | −403 | $9.50 | 94,821 | Form 4 |
| 13 May 2026 | Mano Michael | EVP, CLO&Secretary | Grant or award | +700 | — | 94,664 | Form 4 |
| 13 May 2026 | Paulson Richard A. | President and CEO | Grant or award | +4,920 | — | 271,950 | Form 4 |
| 13 May 2026 | Abate Kristin | Chief Accounting Officer | Grant or award | +121 | — | 23,854 | Form 4 |
| 13 May 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Grant or award | +947 | — | 108,264 | Form 4 |
Names appear as in the filing, surname first. A dash in the price column means the filing reports none, as in grants and gifts.
How to read the table
Only open-market purchases and sales are trades the insider chose to make at the market price, and they are the ones counted in the summary above. Grants, option exercises and shares withheld for tax come from pay plans. A sale marked as a 10b5-1 plan was scheduled in advance under a written plan.
Where each row comes from
From the Form 4 that each executive, director or large shareholder must file with the SEC within two business days of a transaction, read up to 10 November 2026. Each row links to its filing on EDGAR. Only transactions in shares are listed, not derivatives, and amended filings are left out. The accounts of the company are on the Karyopharm Therapeutics page; the method, in data sources.
Information prepared from the Form 4 filings submitted to the SEC, for information purposes only. It is not financial advice or a recommendation to buy or sell. Updated on 12 November 2026.